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Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex

Three new natural products, 3,8-dimethoxy-5,7-dihydroxy-3′,4′-methylenedioxyflavone, 3,6,8-trimethoxy-5,7-dihydroxy-3′,4′-methylenedioxyflavone and 3,6,8,3′,4′-pentamethoxy-5,7-dihydroxyflavone were isolated from Melicope coodeana syn. Euodia simplex (Rutaceae) along with 3,6,3′-trimethoxy-5,7,4′-tr...

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Published in:Phytochemistry (Oxford) 2002-08, Vol.60 (8), p.817-820
Main Authors: Simonsen, Henrik T, Larsen, Michael D, Nielsen, Merete W, Adsersen, Anne, Olsen, Carl Erik, Strasberg, Dominique, Smitt, Ulla W, Jaroszewski, Jerzy W
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container_title Phytochemistry (Oxford)
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creator Simonsen, Henrik T
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description Three new natural products, 3,8-dimethoxy-5,7-dihydroxy-3′,4′-methylenedioxyflavone, 3,6,8-trimethoxy-5,7-dihydroxy-3′,4′-methylenedioxyflavone and 3,6,8,3′,4′-pentamethoxy-5,7-dihydroxyflavone were isolated from Melicope coodeana syn. Euodia simplex (Rutaceae) along with 3,6,3′-trimethoxy-5,7,4′-trihydroxyflavone and 3,3′-dimethoxy-5,7,4′-trihydroxyflavone. The structural assignments are based on 1H and 13C NMR data, including discussion of the chemical shifts of C-2 in 3,5-dihydroxy- and 3-methoxy-5-hydroxyflavones. The presence of highly methoxylated and methylenedioxyflavones is characteristic of the genus Melicope, and the present findings support the recent transfer of Euodia simplex to Melicope. The isolation and structural elucidation of several flavonols, including two methylenedioxyflavones, are presented..
doi_str_mv 10.1016/S0031-9422(02)00083-3
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subjects 13C NMR
Biological and medical sciences
Chemical constitution
Chemotaxonomy
Euodia simplex
Flavonoids - chemistry
Flavonoids - isolation & purification
Fundamental and applied biological sciences. Psychology
Melicope coodeana
Methoxyflavones
Methylenedioxyflavones
Molecular Structure
Plant cytology, morphology, systematics, chorology and evolution
Plant physiology and development
Rutaceae
Rutaceae - chemistry
Réunion Island
Spectrum Analysis
Spermatophyta
Systematics (diagnosis, chromosome numbers)
title Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex
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