Adapting arrays and lab-on-a-chip technology for proteomics

The impact of proteomics as a discovery engine in life science and in drug discovery has increased tremendously over the last seven years. At the same time, proteomics has expanded from the initial trust as a two‐dimensional gel based approach to cover more functional and structural properties of pr...

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Bibliographic Details
Published in:Proteomics (Weinheim) 2002-04, Vol.2 (4), p.373-382
Main Author: Figeys, Daniel
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Antibodies
Biological and medical sciences
Electrophoresis, Gel, Two-Dimensional - methods
Fundamental and applied biological sciences. Psychology
General aspects, investigation methods
Lab-on-a-chip
Mass Spectrometry - instrumentation
Mass Spectrometry - methods
Microfluidics
Protein Array Analysis
Protein arrays
Proteins
Proteins - analysis
Proteins - chemistry
proteomics
Proteomics - instrumentation
Proteomics - methods
Review
Sequence Analysis, Protein
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Summary:The impact of proteomics as a discovery engine in life science and in drug discovery has increased tremendously over the last seven years. At the same time, proteomics has expanded from the initial trust as a two‐dimensional gel based approach to cover more functional and structural properties of proteins. The development of lab‐on‐a‐chip and protein arrays for proteomics will have to evolve with the changes in proteomics to stay relevant. Here, we review the changes in the field of proteomics and their impact on the development in protein arrays and lab‐on‐a‐chip.
ISSN:1615-9853
1615-9861
DOI:10.1002/1615-9861(200204)2:4<373::AID-PROT373>3.0.CO;2-I