Congenital dyserythropoietic anaemia type II: a case study

A 13-year-old girl with chronic anaemia showed features of congenital dyserythropoietic anaemia (CDA) type II. The main clinical and haematological findings were splenomegaly, a mild microcytic anaemia, and numerous bizarre and binucleate normoblasts in the bone marrow. The acidified serum lysis tes...

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Bibliographic Details
Published in:Acta clinica belgica (English ed. Online) 2002-03, Vol.57 (2), p.85-89
Main Authors: De Laere, E, Louwagie, A, Criel, A
Format: Article
Language:English
Subjects:
Adolescent
Anemia, Dyserythropoietic, Congenital - diagnosis
Anemia, Dyserythropoietic, Congenital - genetics
Female
Humans
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Summary:A 13-year-old girl with chronic anaemia showed features of congenital dyserythropoietic anaemia (CDA) type II. The main clinical and haematological findings were splenomegaly, a mild microcytic anaemia, and numerous bizarre and binucleate normoblasts in the bone marrow. The acidified serum lysis test (Ham's test) performed with 5 normal sera was positive. The patient's red blood cells showed a markedly increased expression of the i red blood cell antigen.
ISSN:1784-3286
2295-3337
DOI:10.1179/acb.2002.019