Deduction of paternity index from DNA mixture

Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the...

Full description

Saved in:
Bibliographic Details
Published in:Forensic science international 2002-08, Vol.128 (3), p.105-107
Main Authors: Liao, Xiang Hai, Lau, Tai Shing, Ngan, Karenda Fai Ngor, Wang, Jun
Format: Article
Language:English
Subjects:
Adultery
Biological and medical sciences
Deduction
Deoxyribonucleic acid
DNA
DNA Fingerprinting
DNA mixture
Female
Forensic medicine
Forensic science
Forensic sciences
Gene loci
Genotype
Genotype & phenotype
Genotypes
Humans
Hypotheses
Likelihood Functions
Male
Mathematical Computing
Medical sciences
Mixture distribution
Paternity
Paternity index
Phenotype
Probability
Public health. Hygiene
Public health. Hygiene-occupational medicine
Semen
Tissues
Vagina
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the mother and child, but not that of the alleged father are available. The formula has been used to solve a real case using mother’s vaginal tissue contaminated with semen from alleged father.
ISSN:0379-0738
1872-6283
DOI:10.1016/S0379-0738(02)00170-6