Deduction of paternity index from DNA mixture

Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the...

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Published in:Forensic science international 2002-08, Vol.128 (3), p.105-107
Main Authors: Liao, Xiang Hai, Lau, Tai Shing, Ngan, Karenda Fai Ngor, Wang, Jun
Format: Article
Language:English
Subjects:
Adultery
Biological and medical sciences
Deduction
Deoxyribonucleic acid
DNA
DNA Fingerprinting
DNA mixture
Female
Forensic medicine
Forensic science
Forensic sciences
Gene loci
Genotype
Genotype & phenotype
Genotypes
Humans
Hypotheses
Likelihood Functions
Male
Mathematical Computing
Medical sciences
Mixture distribution
Paternity
Paternity index
Phenotype
Probability
Public health. Hygiene
Public health. Hygiene-occupational medicine
Semen
Tissues
Vagina
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container_title Forensic science international
container_volume 128
creator Liao, Xiang Hai
Lau, Tai Shing
Ngan, Karenda Fai Ngor
Wang, Jun
description Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the mother and child, but not that of the alleged father are available. The formula has been used to solve a real case using mother’s vaginal tissue contaminated with semen from alleged father.
doi_str_mv 10.1016/S0379-0738(02)00170-6
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source ScienceDirect Journals
subjects Adultery
Biological and medical sciences
Deduction
Deoxyribonucleic acid
DNA
DNA Fingerprinting
DNA mixture
Female
Forensic medicine
Forensic science
Forensic sciences
Gene loci
Genotype
Genotype & phenotype
Genotypes
Humans
Hypotheses
Likelihood Functions
Male
Mathematical Computing
Medical sciences
Mixture distribution
Paternity
Paternity index
Phenotype
Probability
Public health. Hygiene
Public health. Hygiene-occupational medicine
Semen
Tissues
Vagina
title Deduction of paternity index from DNA mixture
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