Configurational assignment of alpha-chiral carboxylic acids by complexation to dimeric Zn-porphyrin: host-guest structure, chiral recognition and circular dichroism

A circular dichroic (CD) excition chirality method based on host-guest chiral recognition has been developed to determine the absolute configuration of carboxylic acids with an alpha-stereogenic center; an amide C = O-->Zn coordination, identified by infrared spectroscopy and computations, is inv...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2002-08 (15), p.1590-1591
Main Authors: Proni, Gloria, Pescitelli, Gennaro, Huang, Xuefei, Quraishi, Nazia Q, Nakanishi, Koji, Berova, Nina
Format: Article
Language:English
Subjects:
Carboxylic Acids - chemistry
Models, Molecular
Molecular Conformation
Monte Carlo Method
Porphyrins - chemistry
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Zinc - chemistry
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Summary:A circular dichroic (CD) excition chirality method based on host-guest chiral recognition has been developed to determine the absolute configuration of carboxylic acids with an alpha-stereogenic center; an amide C = O-->Zn coordination, identified by infrared spectroscopy and computations, is involved in this complexation.
ISSN:1359-7345
DOI:10.1039/b204554k