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The effect of pulsed electromagnetic fields on the osteointegration of hydroxyapatite implants in cancellous bone: a morphologic and microstructural in vivo study

Effects of pulsed electromagnetic fields (PEMFs, 75 Hz, 1.6 mT) were investigated in 12 rabbits after placing hydroxyapatite (HA) implants in their femoral condyles. Six animals were stimulated with PEMFs for three consecutive weeks, 6 h/day, while the remaining animals were sham-treated (Control Gr...

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Published in:Journal of orthopaedic research 2002-07, Vol.20 (4), p.756-763
Main Authors: Fini, Milena, Cadossi, Ruggero, Canè, Valerio, Cavani, Francesco, Giavaresi, Gianluca, Krajewski, Adriano, Martini, Lucia, Nicoli Aldini, Nicolò, Ravaglioli, Antonio, Rimondini, Lia, Torricelli, Paola, Giardino, Roberto
Format: Article
Language:English
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Summary:Effects of pulsed electromagnetic fields (PEMFs, 75 Hz, 1.6 mT) were investigated in 12 rabbits after placing hydroxyapatite (HA) implants in their femoral condyles. Six animals were stimulated with PEMFs for three consecutive weeks, 6 h/day, while the remaining animals were sham-treated (Control Group). Rabbits were sacrificed at 3 and 6 weeks (after a 3-week non-stimulation period) for histomorphometric analysis and microhardness testing (at 200, 500, 1000, 2000 μm from the implant) around the implants. Histomorphometric analysis did not highlight any significant changes. On the contrary, there were statistically significant differences between the effects produced by PEMFs and Control Groups ( F=149.70, p
ISSN:0736-0266
1554-527X
DOI:10.1016/S0736-0266(01)00158-9