Prognostic significance of the mode of detection in renal tumours

• Published in: BJU international 2002-09, Vol.90 (4), p.358-363
• Main Authors: Patard, J.‐J., Rodriguez, A., Rioux‐Leclercq, N., Guillé, F., Lobel, B.
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Carcinoma, Renal Cell - diagnosis; Chi-Square Distribution; detection; diagnosis; Female; Follow-Up Studies; Humans; Kidney Neoplasms - diagnosis; Kidneys; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Prognosis; Proportional Hazards Models; renal cell carcinoma; survival; Survival Analysis; Tumors of the urinary system
• ISSN: 1464-4096; 1464-410X
• DOI: 10.1046/j.1464-410X.2002.02910.x

Objective  To evaluate the mode of detection of 400 renal tumours as a prognostic factor compared with the usual clinical and pathological prognostic variables. Patients and methods  The data were reviewed for 400 patients operated for a renal tumour at our institution between 1984 and 1999, analysing the prognostic value of age, sex, tumour size, stage, grade, vein invasion, adrenal gland invasion, lymph node invasion, metastasis, and mode of detection (incidental or not). The survival rates were assessed using the Kaplan‐Meier method and log‐rank test, and the data evaluated using multivariate analysis with the Cox proportional‐hazard model. Results  In all, 151 (38%) renal tumours were discovered incidentally. There was no significant difference in the percentage of renal cell carcinoma found between the groups of patients discovered incidentally or not (94.4% vs 93.9%). Tumours were smaller in the incidental group (5.7 cm vs 8.7 cm, P