Insulin-Dependent Diabetes Mellitus in 2 Male African American Children After Kawasaki Disease

Two children with insulin-dependent diabetes mellitus (IDDM) presented with diabetic ketoacidosis within 4 months of being diagnosed with Kawasaki disease (KD). Both patients were African American males younger than 4 years of age. Immune markers associated with the autoimmune cause of diabetes were...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2002-08, Vol.110 (2), p.e27-e27
Main Authors: Bhowmick, Samar K, Estrada, Benjamin, Rettig, Kenneth R
Format: Article
Language:English
Subjects:
Black or African American
Black People
Child, Preschool
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - diagnosis
Humans
Male
Mucocutaneous Lymph Node Syndrome - complications
Pediatrics
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Summary:Two children with insulin-dependent diabetes mellitus (IDDM) presented with diabetic ketoacidosis within 4 months of being diagnosed with Kawasaki disease (KD). Both patients were African American males younger than 4 years of age. Immune markers associated with the autoimmune cause of diabetes were not detectable in these patients at the time of diagnosis with IDDM. In 1 patient, the immune markers were repeated 6 months after diagnosis but remained negative. Both patients currently require approximately 1 unit of insulin/kg/d. Occurrence of IDDM after KD is rare; we could find no such reports in the English literature. The cause of diabetes in these 2 patients remains elusive, as does the cause of KD.
ISSN:0031-4005
1098-4275
1098-4275
DOI:10.1542/peds.110.2.e27