Studies of Pediatric Liver Transplantation: 2002 update. An overview of demographics, indications, timing, and immunosuppressive practices in pediatric liver transplantation in the United States and Canada

:  Studies of Pediatric Liver Transplantation (SPLIT) was initiated in 1995 for the purpose of collecting comprehensive data from children undergoing liver transplantation. As of May 31, 2002, 1761 children were registered in SPLIT from 38 participating centers in the United States and Canada. This...

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Bibliographic Details
Published in:Pediatric transplantation 2004-06, Vol.8 (3), p.284-294
Main Authors: McDiarmid, S. V., Anand, R., Lindblad, A. S.
Format: Article
Language:English
Subjects:
ABO Blood-Group System
Adolescent
Biological and medical sciences
Canada
Child
Child, Preschool
demographics
Drug Utilization
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
General aspects
Humans
immunosuppression
Immunosuppressive Agents - therapeutic use
indications
Infant
liver
Liver Diseases - surgery
Liver Transplantation - statistics & numerical data
Male
Medical sciences
pediatric
Registries
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Time Factors
timing
Tissue Donors
transplantation
United States
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Summary::  Studies of Pediatric Liver Transplantation (SPLIT) was initiated in 1995 for the purpose of collecting comprehensive data from children undergoing liver transplantation. As of May 31, 2002, 1761 children were registered in SPLIT from 38 participating centers in the United States and Canada. This report focuses on the demographics, primary diagnoses, clinical indications for transplant, and probability of obtaining liver transplantation for the 1187 children receiving a liver transplant after registration in SPLIT. Demographic information is also provided for the 1092 children who received their first ever liver transplantation. For this cohort, we also describe immunosuppressive practices at the time of transplant, and how the use of different medications changes with time.
ISSN:1397-3142
1399-3046
DOI:10.1111/j.1399-3046.2004.00153.x