Effect of Young Barley Leaf Extract and Adlay on Plasma Lipids and LDL Oxidation in Hyperlipidemic Smokers

Forty hyperlipidemic patients, smokers and non-smokers, were studied. Subjects received 15 g young barley leaf extract (BL) or 60 g adlay daily for four weeks. Overnight fasting blood samples were drawn immediately prior to and after four weeks of supplementation. Blood samples were analyzed for pla...

Full description

Saved in:
Bibliographic Details
Published in:Biological & Pharmaceutical Bulletin 2004, Vol.27(6), pp.802-805
Main Authors: Yu, Ya-Mei, Chang, Weng-Cheng, Liu, Chu-Sun, Tsai, Ching-Min
Format: Article
Language:English
Subjects:
adlay
Adult
Aged
Analysis of Variance
barley leaf
Coix
Hordeum
Humans
Hyperlipidemias - blood
Hyperlipidemias - drug therapy
hyperlipidemic smoker
Lipids - blood
Lipoproteins, LDL - blood
low-density lipoprotein (LDL) oxidation
Male
Middle Aged
Oxidation-Reduction - drug effects
Plant Extracts - isolation & purification
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Plant Leaves
plasma lipid
Smoking - blood
Smoking - drug therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Forty hyperlipidemic patients, smokers and non-smokers, were studied. Subjects received 15 g young barley leaf extract (BL) or 60 g adlay daily for four weeks. Overnight fasting blood samples were drawn immediately prior to and after four weeks of supplementation. Blood samples were analyzed for plasma lipid profiles and their susceptibility to low-density lipoprotein (LDL) oxidation. The plasma total and LDL-cholesterol (LDL-C) levels were reduced following treatment with either BL or adlay; furthermore, the lag phase of LDL oxidation increased after either supplementation. However, it seemed that BL had stronger antioxidative effect on the prevention of LDL oxidation than adlay. Our results also indicated that the antioxidative effect was less pronounced in smokers than in non-smokers. Therefore, supplementation with BL or adlay can decrease plasma lipids and inhibit LDL oxidation in hyperlipidemic smokers and/or non-smokers.
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.27.802