Interventional and surgical modalities of treatment for pulmonary arterial hypertension

Beyond medical therapy, different interventional and surgical approaches exist for treatment of pulmonary arterial hypertension (PAH). Atrial septostomy has been applied in patients with lack of response to medical therapy in the absence of other surgical treatment options. With growing experience,...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2004-06, Vol.43 (12), p.S73-S80
Main Authors: Klepetko, Walter, Mayer, Eckhard, Sandoval, Julio, Trulock, Elbert P, Vachiery, Jean-Luc, Dartevelle, Phillippe, Pepke-Zaba, Joanna, Jamieson, Stuart W, Lang, Irene, Corris, Paul
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Catheterization
Embolisms
Endarterectomy
Heart
Heart-Lung Transplantation
Humans
Hypertension, Pulmonary - surgery
Hypertension, Pulmonary - therapy
Medical prognosis
Medical sciences
Mortality
Patient Selection
Pneumology
Pulmonary arteries
Pulmonary Artery - pathology
Pulmonary Artery - surgery
Pulmonary hypertension
Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
Transplants & implants
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Summary:Beyond medical therapy, different interventional and surgical approaches exist for treatment of pulmonary arterial hypertension (PAH). Atrial septostomy has been applied in patients with lack of response to medical therapy in the absence of other surgical treatment options. With growing experience, procedure-related death rates have been reduced to 5.4%, and the most suitable patient group has been identified among patients with a mean right atrial pressure between 10 and 20 mm Hg. Pulmonary endarterectomy is the accepted form of treatment for patients with chronic thromboembolic pulmonary hypertension. Establishing the diagnosis and the classification of the type of lesions by pulmonary angiography is crucial for optimal patient selection. Perioperative mortality rates have been reduced to
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2004.02.039