New risk factors for atherosclerosis and patient risk assessment

Advances in our understanding of the ways in which the traditional cardiovascular risk factors, including standard lipid (eg, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) and nonlipid (eg, hypertension) risk factors, interact to initiate atheroscl...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2004-06, Vol.109 (23 Suppl 1), p.III15-III19
Main Authors: Fruchart, Jean-Charles, Nierman, Melchior C, Stroes, Erik S G, Kastelein, John J P, Duriez, Patrick
Format: Article
Language:English
Subjects:
Adult
Aged
Arteriosclerosis - blood
Arteriosclerosis - epidemiology
Arteriosclerosis - genetics
C-Reactive Protein - analysis
Cardiovascular Diseases - epidemiology
Cohort Studies
Comorbidity
Diabetes Mellitus - epidemiology
Female
Glucose Intolerance - epidemiology
Humans
Hyperhomocysteinemia - epidemiology
Hypertriglyceridemia - epidemiology
Inflammation - epidemiology
Lipoprotein(a) - blood
Male
Metabolic Syndrome - blood
Metabolic Syndrome - epidemiology
Middle Aged
Practice Guidelines as Topic
Risk Assessment - methods
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Advances in our understanding of the ways in which the traditional cardiovascular risk factors, including standard lipid (eg, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) and nonlipid (eg, hypertension) risk factors, interact to initiate atherosclerosis and promote the development of cardiovascular disease have enhanced our ability to assess risk in the individual patient. In addition, the ongoing identification and understanding of so-called novel risk factors may further improve our ability to predict future risk when these are included along with the classic risk factors in assessing the global risk profile. This review briefly summarizes the evidence that some newer risk factors, including impaired fasting glucose, triglycerides and triglyceride-rich lipoprotein remnants, lipoprotein(a), homocysteine, and high-sensitivity C-reactive protein, contribute to an increased risk of coronary and cardiovascular diseases.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.0000131513.33892.5b