Clinical validation of glucose pump test (GPT) compared with ultrasound dilution technology in arteriovenous graft surveillance

Background. Blood flow (Qa) measurements are an important step in the surveillance protocol of haemodialysis vascular access (VA). The glucose pump test (GPT) is a new test for Qa measurement based on the dilution of a constant glucose infusion. The aim of this study is to verify the clinical accura...

Full description

Saved in:
Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2004-07, Vol.19 (7), p.1835-1841
Main Authors: Magnasco, Alberto, Bacchini, Giuseppe, Cappello, Antonio, La Milia, Vincenzo, Brezzi, Brigida, Messa, PierGiorgio, Locatelli, Francesco
Format: Article
Language:English
Subjects:
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Arteriovenous Shunt, Surgical
Biological and medical sciences
Blood Glucose - analysis
Catheters, Indwelling
colour Doppler ultrasound
Diseases of the cardiovascular system
Emergency and intensive care: renal failure. Dialysis management
Female
haemodialysis
Humans
Intensive care medicine
Male
Medical sciences
Prospective Studies
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Regional Blood Flow
Renal Dialysis
Reproducibility of Results
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Ultrasonography, Doppler, Color
ultrasound dilution technology
vascular access
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background. Blood flow (Qa) measurements are an important step in the surveillance protocol of haemodialysis vascular access (VA). The glucose pump test (GPT) is a new test for Qa measurement based on the dilution of a constant glucose infusion. The aim of this study is to verify the clinical accuracy of GPT in a graft surveillance protocol with sequential Qa measurements. Methods. In 30 chronic haemodialysis patients with graft, we compared monthly sequential Qa measurements performed with GPT in pre-dialysis and the ultrasound dilution technique (HD01 device Transonic Systems Inc., USA) during dialysis. The colour Doppler ultrasonography study (CDU) was our reference standard for the diagnosis of stenosis. The endpoints were the graft thrombosis or PTA treatment. Results. According to the K/DOQI guidelines we could identify the thrombosis high-risk grafts when Qa was 600 ml/min and ΔQa
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfh292