Influence of age on clinical course, management and mortality of acute myocardial infarction in the Spanish population

• Published in: International journal of cardiology 2002-10, Vol.85 (2), p.285-296
• Main Authors: Ruiz-Bailén, Manuel, Aguayo de Hoyos, Eduardo, Ramos-Cuadra, José Ángel, Dı́az-Castellanos, Miguel Ángel, Issa-Khozouz, Ziad, Reina-Toral, Antonio, López-Martı́nez, Asunción, Calatrava-López, Jesús, Laynez-Bretones, Francisco, Castillo-Parra, Juan Carlos, De La Torre-Prados, Marı́a Victoria
• Format: Article
• Language: English
• Subjects: Acute myocardial infarction; Adolescent; Adult; Age; Age Factors; Aged; Aged, 80 and over; Biological and medical sciences; Cardiology. Vascular system; Child; Cohort Studies; Coronary heart disease; Elderly; Female; Heart; Humans; Incidence; Length of Stay; Male; Medical sciences; Middle Aged; Mortality; Myocardial Infarction - complications; Myocardial Infarction - mortality; Myocardial Infarction - therapy; Prognosis; Retrospective Studies; Risk Factors; Spain; Statistics as Topic; Thrombolysis; Thrombolytic Therapy - statistics & numerical data
• ISSN: 0167-5273; 1874-1754
• DOI: 10.1016/S0167-5273(02)00187-0

Background: To assess age-related differences in cardiovascular risk factors, clinical course and management of patients with acute myocardial infarction (AMI) in intensive care (ICU) or coronary care units (CCU). Methods: A retrospective cohort study was conducted of all AMI patients listed in the ARIAM register (Analysis of Delay in AMI), a multi-centre register in which 119 Spanish hospitals participated. The study period was from January 1995 to January 2001. A univariate analysis was carried out to evaluate differences between different age groups. Multivariate analysis was used to assess whether age difference was an independent predisposing factor for mortality and for differences in patient management. Results: 17,761 patients were admitted to the ICUs/CCUs with a diagnosis of AMI. The distribution by ages was: 84 years, 604 (3.4%) ( P