Neuroimaging in lissencephaly type I

The CT scan's of 22 patients with lissencephaly type I, a severe developmental disorder of the cerebral cortex, were studied. In 6 patients a magnetic resonance (MR), scan was also performed. The CT and MR scans of the lissencephaly patients were compared to a control group consisting of 49 pat...

Full description

Saved in:
Bibliographic Details
Published in:Neuroradiology 1991-01, Vol.33 (3), p.230-233
Main Authors: DE RIJK-VAN ANDEL, J. F, VAN DER KNAAP, M. S, VALK, J, ARTZ, W. F. M
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Cerebral Cortex - abnormalities
Cerebral Cortex - diagnostic imaging
Cerebral Cortex - pathology
Child
Female
Humans
Infant
Infant, Newborn
Magnetic Resonance Imaging
Male
Malformations of the nervous system
Medical sciences
Neurology
Tomography, X-Ray Computed
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The CT scan's of 22 patients with lissencephaly type I, a severe developmental disorder of the cerebral cortex, were studied. In 6 patients a magnetic resonance (MR), scan was also performed. The CT and MR scans of the lissencephaly patients were compared to a control group consisting of 49 patients with a normal CT or MR scan. In lissencephaly the cortical thickness was always larger than 10 mm, as compared to less than 7 mm in the normal situation. In lissencephaly the WSF/DSF index (with/depth of the sylvian fissure) was always larger than 0.29, while in the normal situation less than 0.25.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00588223