Pregnancy with acute intermittent porphyria: A case report and review of literature

Acute intermittent porphyria (AIP) is an inherited disorder characterized by partial defects in the heme biosynthetic pathway. Although its association with pregnancy is rare, it presents the obstetrician with challenging problems especially in labor management, as one of the obstetrical life line d...

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Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2002-06, Vol.28 (3), p.160-162
Main Authors: Aggarwal, Neelam, Bagga, Rashmi, Sawhney, Harjit, Suri, Vanita, Vasishta, Kala
Format: Article
Language:English
Subjects:
acute intermittent porphyria
Adult
Female
Humans
porphobilinogen
Porphyria, Acute Intermittent - therapy
porphyrogenic drugs
Pregnancy
Pregnancy Complications - therapy
Pregnancy Outcome
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Summary:Acute intermittent porphyria (AIP) is an inherited disorder characterized by partial defects in the heme biosynthetic pathway. Although its association with pregnancy is rare, it presents the obstetrician with challenging problems especially in labor management, as one of the obstetrical life line drugs (methergin) is contraindicated for use in these patients. We hereby present a case of AIP who had an uneventful pregnancy with a good neonatal outcome.
ISSN:1341-8076
1447-0756
DOI:10.1046/j.1341-8076.2002.00024.x