Diet and cancer: assessing the risk

Globally, colorectal cancer (CRC) is a leading cause of mortality from malignant disease. Case–control and cohort studies provide strong support for a role of diet in the aetiology of CRC. However to establish causal relationships and to identify more precisely the dietary components involved, inter...

Full description

Saved in:
Bibliographic Details
Published in:British journal of nutrition 2002-09, Vol.88 (S1), p.s73-s87
Main Authors: Gill, C. I. R., Rowland, I. R.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biomarkers
Biomarkers, Tumor - analysis
Cancer research
Cell Transformation, Neoplastic
Colorectal cancer
Colorectal carcinoma
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - etiology
Diet
Diet - adverse effects
Epidemiology
Etiology
Fatty acids
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Kinases
Medical research
Medical sciences
Mortality
Nutrition research
Other diseases. Semiology
Risk Assessment
Risk Factors
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33
cites cdi_FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33
container_end_page s87
container_issue S1
container_start_page s73
container_title British journal of nutrition
container_volume 88
creator Gill, C. I. R.
Rowland, I. R.
description Globally, colorectal cancer (CRC) is a leading cause of mortality from malignant disease. Case–control and cohort studies provide strong support for a role of diet in the aetiology of CRC. However to establish causal relationships and to identify more precisely the dietary components involved, intervention studies in human subjects are required. Cancer is an impractical endpoint in terms of numbers, cost, study duration and ethical considerations. Consequently, intermediate biomarkers of the disease are required. This review aims to provide an overview of the intermediate endpoints available for the study of CRC, particularly non-invasive faecal biomarkers. Examples of their use in dietary intervention studies are given.
doi_str_mv 10.1079/BJN2002632
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72066855</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1079_BJN2002632</cupid><sourcerecordid>72066855</sourcerecordid><originalsourceid>FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33</originalsourceid><addsrcrecordid>eNpt0E1LxDAQBuAgiruuXvwBUhE9iNVM0qSJN12_WfSi5zJN07Vrt12T9uC_t8sWCuJpGHh4Z3gJOQR6CTTWV7cvr4xSJjnbImOIYhEyKdk2GVNK4xAgEiOy5_2iWxVQvUtGwBgIUHJMTu4K2wRYZYHBylh3HaD31vuimgfNpw1c4b_2yU6OpbcH_ZyQj4f79-lTOHt7fJ7ezEIjQDehVEoLzHTKKJo8B-QZF1JrQLCYca5ULk0kMokppDRVsZKRRip5bCU3OecTcrbJXbn6u7W-SZaFN7YssbJ165OYUSmVEB08_gMXdeuq7rdEaQDOYtmZ840xrvbe2TxZuWKJ7icBmqxrS4baOnzUB7bp0mYD7XvqwGkP0Bssc9eVVfjBcS1Bx-ugi_4qLlNXZHM7vPbP3V-MPH8P</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>89113276</pqid></control><display><type>article</type><title>Diet and cancer: assessing the risk</title><source>Free Full-Text Journals in Chemistry</source><source>Cambridge University Press:JISC Collections:Full Collection Digital Archives (STM and HSS) (218 titles)</source><creator>Gill, C. I. R. ; Rowland, I. R.</creator><creatorcontrib>Gill, C. I. R. ; Rowland, I. R.</creatorcontrib><description>Globally, colorectal cancer (CRC) is a leading cause of mortality from malignant disease. Case–control and cohort studies provide strong support for a role of diet in the aetiology of CRC. However to establish causal relationships and to identify more precisely the dietary components involved, intervention studies in human subjects are required. Cancer is an impractical endpoint in terms of numbers, cost, study duration and ethical considerations. Consequently, intermediate biomarkers of the disease are required. This review aims to provide an overview of the intermediate endpoints available for the study of CRC, particularly non-invasive faecal biomarkers. Examples of their use in dietary intervention studies are given.</description><identifier>ISSN: 0007-1145</identifier><identifier>EISSN: 1475-2662</identifier><identifier>DOI: 10.1079/BJN2002632</identifier><identifier>PMID: 12215186</identifier><identifier>CODEN: BJNUAV</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Biological and medical sciences ; Biomarkers ; Biomarkers, Tumor - analysis ; Cancer research ; Cell Transformation, Neoplastic ; Colorectal cancer ; Colorectal carcinoma ; Colorectal Neoplasms - diagnosis ; Colorectal Neoplasms - etiology ; Diet ; Diet - adverse effects ; Epidemiology ; Etiology ; Fatty acids ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Kinases ; Medical research ; Medical sciences ; Mortality ; Nutrition research ; Other diseases. Semiology ; Risk Assessment ; Risk Factors ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>British journal of nutrition, 2002-09, Vol.88 (S1), p.s73-s87</ispartof><rights>Copyright © The Nutrition Society 2002</rights><rights>2002 INIST-CNRS</rights><rights>The Nutrition Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33</citedby><cites>FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007114502001824/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925,55689</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=13961972$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12215186$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gill, C. I. R.</creatorcontrib><creatorcontrib>Rowland, I. R.</creatorcontrib><title>Diet and cancer: assessing the risk</title><title>British journal of nutrition</title><addtitle>Br J Nutr</addtitle><description>Globally, colorectal cancer (CRC) is a leading cause of mortality from malignant disease. Case–control and cohort studies provide strong support for a role of diet in the aetiology of CRC. However to establish causal relationships and to identify more precisely the dietary components involved, intervention studies in human subjects are required. Cancer is an impractical endpoint in terms of numbers, cost, study duration and ethical considerations. Consequently, intermediate biomarkers of the disease are required. This review aims to provide an overview of the intermediate endpoints available for the study of CRC, particularly non-invasive faecal biomarkers. Examples of their use in dietary intervention studies are given.</description><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>Biomarkers, Tumor - analysis</subject><subject>Cancer research</subject><subject>Cell Transformation, Neoplastic</subject><subject>Colorectal cancer</subject><subject>Colorectal carcinoma</subject><subject>Colorectal Neoplasms - diagnosis</subject><subject>Colorectal Neoplasms - etiology</subject><subject>Diet</subject><subject>Diet - adverse effects</subject><subject>Epidemiology</subject><subject>Etiology</subject><subject>Fatty acids</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Kinases</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Nutrition research</subject><subject>Other diseases. Semiology</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0007-1145</issn><issn>1475-2662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNpt0E1LxDAQBuAgiruuXvwBUhE9iNVM0qSJN12_WfSi5zJN07Vrt12T9uC_t8sWCuJpGHh4Z3gJOQR6CTTWV7cvr4xSJjnbImOIYhEyKdk2GVNK4xAgEiOy5_2iWxVQvUtGwBgIUHJMTu4K2wRYZYHBylh3HaD31vuimgfNpw1c4b_2yU6OpbcH_ZyQj4f79-lTOHt7fJ7ezEIjQDehVEoLzHTKKJo8B-QZF1JrQLCYca5ULk0kMokppDRVsZKRRip5bCU3OecTcrbJXbn6u7W-SZaFN7YssbJ165OYUSmVEB08_gMXdeuq7rdEaQDOYtmZ840xrvbe2TxZuWKJ7icBmqxrS4baOnzUB7bp0mYD7XvqwGkP0Bssc9eVVfjBcS1Bx-ugi_4qLlNXZHM7vPbP3V-MPH8P</recordid><startdate>20020901</startdate><enddate>20020901</enddate><creator>Gill, C. I. R.</creator><creator>Rowland, I. R.</creator><general>Cambridge University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20020901</creationdate><title>Diet and cancer: assessing the risk</title><author>Gill, C. I. R. ; Rowland, I. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological and medical sciences</topic><topic>Biomarkers</topic><topic>Biomarkers, Tumor - analysis</topic><topic>Cancer research</topic><topic>Cell Transformation, Neoplastic</topic><topic>Colorectal cancer</topic><topic>Colorectal carcinoma</topic><topic>Colorectal Neoplasms - diagnosis</topic><topic>Colorectal Neoplasms - etiology</topic><topic>Diet</topic><topic>Diet - adverse effects</topic><topic>Epidemiology</topic><topic>Etiology</topic><topic>Fatty acids</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Kinases</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Nutrition research</topic><topic>Other diseases. Semiology</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gill, C. I. R.</creatorcontrib><creatorcontrib>Rowland, I. R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest_Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Agriculture Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gill, C. I. R.</au><au>Rowland, I. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diet and cancer: assessing the risk</atitle><jtitle>British journal of nutrition</jtitle><addtitle>Br J Nutr</addtitle><date>2002-09-01</date><risdate>2002</risdate><volume>88</volume><issue>S1</issue><spage>s73</spage><epage>s87</epage><pages>s73-s87</pages><issn>0007-1145</issn><eissn>1475-2662</eissn><coden>BJNUAV</coden><abstract>Globally, colorectal cancer (CRC) is a leading cause of mortality from malignant disease. Case–control and cohort studies provide strong support for a role of diet in the aetiology of CRC. However to establish causal relationships and to identify more precisely the dietary components involved, intervention studies in human subjects are required. Cancer is an impractical endpoint in terms of numbers, cost, study duration and ethical considerations. Consequently, intermediate biomarkers of the disease are required. This review aims to provide an overview of the intermediate endpoints available for the study of CRC, particularly non-invasive faecal biomarkers. Examples of their use in dietary intervention studies are given.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>12215186</pmid><doi>10.1079/BJN2002632</doi><tpages>15</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0007-1145
ispartof British journal of nutrition, 2002-09, Vol.88 (S1), p.s73-s87
issn 0007-1145
1475-2662
language eng
recordid cdi_proquest_miscellaneous_72066855
source Free Full-Text Journals in Chemistry; Cambridge University Press:JISC Collections:Full Collection Digital Archives (STM and HSS) (218 titles)
subjects Biological and medical sciences
Biomarkers
Biomarkers, Tumor - analysis
Cancer research
Cell Transformation, Neoplastic
Colorectal cancer
Colorectal carcinoma
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - etiology
Diet
Diet - adverse effects
Epidemiology
Etiology
Fatty acids
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Kinases
Medical research
Medical sciences
Mortality
Nutrition research
Other diseases. Semiology
Risk Assessment
Risk Factors
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
title Diet and cancer: assessing the risk
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T22%3A28%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diet%20and%20cancer:%20assessing%20the%20risk&rft.jtitle=British%20journal%20of%20nutrition&rft.au=Gill,%20C.%20I.%20R.&rft.date=2002-09-01&rft.volume=88&rft.issue=S1&rft.spage=s73&rft.epage=s87&rft.pages=s73-s87&rft.issn=0007-1145&rft.eissn=1475-2662&rft.coden=BJNUAV&rft_id=info:doi/10.1079/BJN2002632&rft_dat=%3Cproquest_cross%3E72066855%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c519t-68895ad9b20acff1a3d356991a1ead3388f6c45d6ab1b0b878649a0637e63cf33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=89113276&rft_id=info:pmid/12215186&rft_cupid=10_1079_BJN2002632&rfr_iscdi=true