Point-of-care testing of blood glucose in the neonatal unit using the AVL Omni 9 analyser

• Published in: Annals of clinical biochemistry 2002-09, Vol.39 (5), p.509-512
• Main Authors: NEWMAN, Julie D, PECACHE, Nerissa S, BARFIELD, Charles P, BALAZS, Nicholas D. H
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Biosensing Techniques - instrumentation; Biosensing Techniques - methods; Blood Glucose - analysis; Calibration; Hematocrit; Humans; Hypoglycemia - blood; Hypoglycemia - diagnosis; Infant, Newborn - blood; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Metabolic diseases; Nurseries, Hospital; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Point-of-Care Systems; Quality Control; Regression Analysis
• ISSN: 0004-5632; 1758-1001
• DOI: 10.1258/000456302320314539

Background: Blood glucose measurements in newborns at risk of hypoglycaemia are an essential part of their medical management. Blood glucose measurements obtained by point-of-care testing using an AVL Omni 9 blood gas and metabolite analyser were compared with those obtained in the central laboratory using a Dade Dimension RXL analyser. Methods: Blood glucose was measured at the point of care by nursing staff using an AVL Omni 9 blood gas and metabolite analyser and compared to results obtained in the central laboratory using a DADE Dimension RXL analyser. In total, 123 samples were taken from 114 babies admitted to the neonatal unit. Results: The limits of agreement between the AVL Omni 9 and the central laboratory were 0·0±0·6 mmol/L for glucose values between 0·5 and 13 mmol/L. Regression analysis showed: AVL Omni 9 glucose = 0·977 x plasma glucose+0·14. There was also a good correlation (r=0·92) between the AVL Omni 9 and the DADE Dimension RXL analyser for glucose values