Diclofenac sodium and spasmolytic drugs in the treatment of ureteral colic: a comparative study

Forty-nine patients with ureteral colic were included in this prospective double-blind study investigating the analgesic efficacy and side effects of a prostaglandin synthetase inhibitor Diclofenac sodium (Voltaren) versus a spasmolytic drug Tropenzilium bromide (Palerol). The analgesic efficacy and...

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Bibliographic Details
Published in:International urology and nephrology 1991-05, Vol.23 (3), p.227-230
Main Authors: Başar, I, Bircan, K, Taşar, C, Ergen, A, Cakmak, F, Remzi, D
Format: Article
Language:English
Subjects:
Adult
Analgesics
Colic - drug therapy
Diclofenac - therapeutic use
Dipyrone - therapeutic use
Double-Blind Method
Drug Combinations
Female
Humans
Male
Nifedipine - pharmacology
Nifedipine - therapeutic use
Parasympatholytics - therapeutic use
Prospective Studies
Pyrazoles - therapeutic use
Tropanes - therapeutic use
Ureteral Diseases - drug therapy
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Summary:Forty-nine patients with ureteral colic were included in this prospective double-blind study investigating the analgesic efficacy and side effects of a prostaglandin synthetase inhibitor Diclofenac sodium (Voltaren) versus a spasmolytic drug Tropenzilium bromide (Palerol). The analgesic efficacy and side effects of the calcium antagonist Nifedipine (Nidilat) applied sublingually in ureteral colic were also investigated. It was concluded that diclofenac sodium was more efficient for relieving pain due to acute ureteral obstruction and had fewer side effects than spasmolytic drugs. Nifedipine proved to have an analgesic effect equivalent to that of Tropenzilium bromide.
ISSN:0301-1623
1573-2584
DOI:10.1007/BF02550416