Serum Lipoprotein (a) Levels in Men with Peripheral Vascular Disease

The authors quantified serum lipoprotein (a) (Lp) (a) by enzymoimmunoanalysis in 86 outpatient men suffering peripheral vascular disease (PVD) and in 53 age-matched healthy men. They further measured serum cholesterol, serum triglycerides, low density lipoproteins-cholesterol, high density lipoprote...

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Bibliographic Details
Published in:Angiology 1991-08, Vol.42 (8), p.659-664
Main Authors: Nogués, Xavier, Seni, Mariano, Pedro-Botet, Juan, Rubiés-Prat, Juan, Vidal-Barraquer, Francesc
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Biomarkers - blood
Blood and lymphatic vessels
Cardiology. Vascular system
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Humans
Lipids - blood
Lipoprotein(a)
Lipoproteins - blood
Male
Medical sciences
Middle Aged
Risk Factors
Vascular Diseases - blood
Vascular Diseases - epidemiology
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Summary:The authors quantified serum lipoprotein (a) (Lp) (a) by enzymoimmunoanalysis in 86 outpatient men suffering peripheral vascular disease (PVD) and in 53 age-matched healthy men. They further measured serum cholesterol, serum triglycerides, low density lipoproteins-cholesterol, high density lipoproteins (HDL)-cholesterol and serum apolipoprotein B. Serum triglycerides were significantly increased in patients with PVD versus controls (148 ± 8 and 114 ± 7 mg/dL, mean ± SEM). HDL-cholesterol levels were significantly lower in patients versus controls (36 ± 1 and 43 ± 2 mg/dL, respectively). Serum Lp(a) levels in patients with PVD were 20 ± 2 mg/dL, whereas in controls they were 16 ± 3 (p: NS). Serum Lp(a) concentrations were identical in smoker and nonsmoker patients. There was no correlation between Lp(a) concentration and the other lipid parameters. Conversely, as occurs in coronary heart disease and in cerebrovascular disease, Lp(a) does not seem to be a marker for PVD, although a trend toward a higher mean levels was found.
ISSN:0003-3197
1940-1574
DOI:10.1177/000331979104200809