Epilepsia partialis continua—a clinical and electroencephalography study

Epilepsia partialis continua (EPC) is a rare type of localization-related motor epilepsy. Clinical spectrum, electroencephalography (EEG) characteristics and various prognostic factors in EPC were studied in 20 patients. Patients who fulfilled the criteria for EPC between the years 1985 and 1999 wer...

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Bibliographic Details
Published in:Seizure (London, England) England), 2002-10, Vol.11 (7), p.437-441
Main Authors: Pandian, J.D., Thomas, S.V., Santoshkumar, B., Radhakrishnan, K., Sarma, P.S., Joseph, S., Kesavadas, C.
Format: Article
Language:English
Subjects:
aetiology
Aged
Brain - pathology
Brain - physiopathology
Child
Child, Preschool
Electroencephalography
Encephalitis - complications
Encephalitis, Viral - complications
EPC
Epilepsies, Partial - diagnosis
Epilepsies, Partial - drug therapy
Epilepsies, Partial - physiopathology
Female
Functional Laterality - physiology
Humans
Infant
Magnetic Resonance Imaging
Male
Middle Aged
prognosis
Prospective Studies
Rasmussen’s encephalitis
Retrospective Studies
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Summary:Epilepsia partialis continua (EPC) is a rare type of localization-related motor epilepsy. Clinical spectrum, electroencephalography (EEG) characteristics and various prognostic factors in EPC were studied in 20 patients. Patients who fulfilled the criteria for EPC between the years 1985 and 1999 were included in this retrospective and prospective study. The mean age was 18 years (range 5 months–70 years). Eleven patients (55%) had Type 1 EPC and in the remaining nine (45%) patients there were features of Type 2 EPC. Among children Rasmussen’s encephalitis and viral encephalitis were the commonest cause for EPC. Encephalitis and vascular aetiology were frequently observed in adults. Tuberculous meningitis and tuberculomas occurred evenly in both the groups. The cause was unknown in two cases. Focal EEG abnormalities commonly consisted of discrete spikes, sharp waves (or) slow wave activity and periodic lateralized epileptiform discharges. The mean duration of follow up was 9.6 months with a range between 1 month and 4 years. Cognitive decline, motor deficits and pharmacoresistance to drugs were significantly seen among children with Type 2 EPC. Patients with Type 1 EPC had mild impairment of functional status with good response to treatment. The long-term prognosis depends upon the underlying cause.
ISSN:1059-1311
1532-2688
DOI:10.1053/seiz.2001.0646