Adenotonsillectomy in children with von Willebrand's disease: how and when. A case report with review of the literature

The presence of coagulation pathology in children who are candidates for adenotonsillectomy (AT) is a challenge to the otolaryngologist. von Willebrand's disease (vWD) is the most common hereditary coagulopathy and is due to a quantitative and/or qualitative deficiency of von Willebrand's...

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Bibliographic Details
Published in:International journal of pediatric otorhinolaryngology 2002-09, Vol.65 (3), p.253-256
Main Authors: Berlucchi, Marco, Tomenzoli, Davide, Nicolai, Piero, Lusk, Rodney P
Format: Article
Language:English
Subjects:
Adenoidectomy
Adenotonsillectomy
Biological and medical sciences
Bleeding disorder
Blood Loss, Surgical - prevention & control
Chemotherapy, Adjuvant
Child, Preschool
Childhood disease
DDAVP
Deamino Arginine Vasopressin - therapeutic use
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Hemostatics - therapeutic use
Humans
Male
Medical sciences
Non tumoral diseases
Otorhinolaryngology. Stomatology
Postoperative Hemorrhage - prevention & control
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the upper aerodigestive tract
Time Factors
Tonsillectomy
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
von Willebrand Diseases - complications
von Willebrand Diseases - drug therapy
von Willebrand's disease
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Summary:The presence of coagulation pathology in children who are candidates for adenotonsillectomy (AT) is a challenge to the otolaryngologist. von Willebrand's disease (vWD) is the most common hereditary coagulopathy and is due to a quantitative and/or qualitative deficiency of von Willebrand's factor (vWF). In recent years, the administration of 1-deamino-8- d-arginine vasopressin (DDAVP) has been recommended as coadjuvant therapy for surgical procedure. This synthetic hormone promotes the release of vWF and factor VIII from endothelial cells. In this report, the authors describe the history of a child with vWD undergoing successful AT after administration of DDAVP. Furthermore, a review of the literature with particular emphasis on the use of DDAVP is made.
ISSN:0165-5876
1872-8464
DOI:10.1016/S0165-5876(02)00179-9