A laboratory study of an inactivated bivalent iron restricted Salmonella enterica serovars Enteritidis and Typhimurium dual vaccine against Typhimurium challenge in chickens

A commercial inactivated iron restricted Salmonella Typhimurium and Salmonella Enteritidis vaccine was used to vaccinate chicks at 1 day and again at 4 weeks of age, with challenge by a high and a low dose of S. Typhimurium given either orally or by contact with seeder birds inoculated orally with a...

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Bibliographic Details
Published in:Veterinary microbiology 2002-10, Vol.89 (2), p.167-179
Main Authors: Clifton-Hadley, F.A, Breslin, M, Venables, L.M, Sprigings, K.A, Cooles, S.W, Houghton, S, Woodward, M.J
Format: Article
Language:English
Subjects:
Animals
Antibodies, Bacterial - blood
Bacteriology
Biological and medical sciences
Challenge models
Chicken-bacteria
Chickens
Cloaca - microbiology
Colonisation
Colony Count, Microbial - veterinary
Enzyme-Linked Immunosorbent Assay - veterinary
Female
Fundamental and applied biological sciences. Psychology
Iron - immunology
Microbiology
Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
Poultry Diseases - immunology
Poultry Diseases - microbiology
Poultry Diseases - prevention & control
Random Allocation
Salenvac ®T
Salmonella enterica serotypes Enteritidis and Typhimurium
Salmonella enteritidis - immunology
Salmonella typhimurium - immunology
Salmonella Vaccines - immunology
Salmonella Vaccines - standards
Statistics, Nonparametric
Vaccination - veterinary
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
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Summary:A commercial inactivated iron restricted Salmonella Typhimurium and Salmonella Enteritidis vaccine was used to vaccinate chicks at 1 day and again at 4 weeks of age, with challenge by a high and a low dose of S. Typhimurium given either orally or by contact with seeder birds inoculated orally with a high dose of S. Typhimurium. In all three challenge regimes, the shedding of challenge strain was reduced significantly ( p
ISSN:0378-1135
1873-2542
DOI:10.1016/S0378-1135(02)00169-4