Prevalence of hypothyroidism in patients with polymyalgia rheumatica and giant cell arteritis

The prevalence of thyroid disease and thyroid autoantibodies was evaluated in 367 patients with polymyalgia rheumatica (PMR) and/or giant cell arteritis (GCA). Thirty-seven patients had antibodies to thyroid microsomes or thyroglobulin; 18 had hypothyroidism requiring thyroxine replacement therapy....

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Bibliographic Details
Published in:British journal of rheumatology 1991-10, Vol.30 (5), p.349-351
Main Authors: BOWNESS, P, SHOTLIFF, K, MIDDLEMISS, A, MYLES, A. B
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Autoantibodies - analysis
Autoimmune Diseases - complications
Autoimmune Diseases - epidemiology
Autoimmune Diseases - immunology
Biological and medical sciences
England - epidemiology
Female
Giant Cell Arteritis - complications
Humans
Hypothyroidism - complications
Hypothyroidism - epidemiology
Hypothyroidism - immunology
Male
Medical sciences
Microsomes - immunology
Middle Aged
Polymyalgia Rheumatica - complications
Prevalence
Prospective Studies
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Thyroglobulin - immunology
Thyroid Gland - immunology
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Summary:The prevalence of thyroid disease and thyroid autoantibodies was evaluated in 367 patients with polymyalgia rheumatica (PMR) and/or giant cell arteritis (GCA). Thirty-seven patients had antibodies to thyroid microsomes or thyroglobulin; 18 had hypothyroidism requiring thyroxine replacement therapy. The prevalence of hypothyroidism (4.9%) was significantly greater than that found in 84 control subjects.
ISSN:0263-7103
1460-2172