Anti-thyroid microsomal antibody in synovial fluid as a revealing feature of seronegative autoimmune thyroiditis

Two cases of recurrent monoarthritis are described in which antithyroid microsomal (antiMi) autoantibody (Ab) was found in synovial fluid (SF) before any clinical or serological evidence of thyroid disease. Subsequently, the follow-up of the two patients showed the appearance of thyroiditis within 2...

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Bibliographic Details
Published in:Clinical rheumatology 1991-06, Vol.10 (2), p.181-183
Main Authors: Punzi, L, Schiavon, F, Ramonda, R, Cavasin, F, Ruffatti, A, Todesco, S
Format: Article
Language:English
Subjects:
Adult
Autoantibodies - immunology
Female
Humans
Microsomes - immunology
Middle Aged
Synovial Fluid - immunology
Thyroid Gland - immunology
Thyroiditis, Autoimmune - immunology
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Summary:Two cases of recurrent monoarthritis are described in which antithyroid microsomal (antiMi) autoantibody (Ab) was found in synovial fluid (SF) before any clinical or serological evidence of thyroid disease. Subsequently, the follow-up of the two patients showed the appearance of thyroiditis within 2-5 years. The presence of anti-Mi Ab in SF might anticipate the appearance of autoimmune thyroiditis even in the absence of serum detectable antithyroid Ab, as was later observed in these two cases.
ISSN:0770-3198
1434-9949
DOI:10.1007/BF02207661