Augmented reality guidance for needle biopsies: An initial randomized, controlled trial in phantoms

• Published in: Medical image analysis 2002-09, Vol.6 (3), p.313-320
• Main Authors: Rosenthal, Michael, State, Andrei, Lee, Joohi, Hirota, Gentaro, Ackerman, Jeremy, Keller, Kurtis, Pisano, Etta D, Jiroutek, Michael, Muller, Keith, Fuchs, Henry
• Format: Article
• Language: English
• Subjects: Augmented reality; Biopsy, Needle - instrumentation; Biopsy, Needle - methods; Breast biopsy; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - pathology; Computer Graphics; Equipment Design; Humans; Imaging, Three-Dimensional - instrumentation; Imaging, Three-Dimensional - methods; Models, Anatomic; Needle biopsy; Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography, Mammary - instrumentation; Ultrasonography, Mammary - methods; Ultrasound guidance; User-Computer Interface
• ISSN: 1361-8415; 1361-8423
• DOI: 10.1016/S1361-8415(02)00088-9

We report the results of a randomized, controlled trial to compare the accuracy of standard ultrasound-guided needle biopsy to biopsies performed using a 3D Augmented Reality (AR) guidance system. A board-certified radiologist conducted 50 core biopsies of breast phantoms, with biopsies randomly assigned to one of the methods in blocks of five biopsies each. The raw ultrasound data from each biopsy was recorded. Another board-certified radiologist, blinded to the actual biopsy guidance mechanism, evaluated the ultrasound recordings and determined the distance of the biopsy from the ideal position. A repeated measures analysis of variance indicated that the head-mounted display method led to a statistically significantly smaller mean deviation from the desired target than did the standard display method (2.48 mm for control versus 1.62 mm for augmented reality, p