Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence

A series of six, cationic, zwitterionic and anionic Eu complexes has been examined for the analysis of hydrogencarbonate concentration in the intracellular and extracellular ranges; an anionic complex incorporating three glutarate residues and a sensitising acridone chromophore (lambda exc = 410 nm)...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2002-01 (17), p.1930-1931
Main Authors: Bretonnière, Yann, Cann, Martin J, Parker, David, Slater, Rachel
Format: Article
Language:English
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Summary:A series of six, cationic, zwitterionic and anionic Eu complexes has been examined for the analysis of hydrogencarbonate concentration in the intracellular and extracellular ranges; an anionic complex incorporating three glutarate residues and a sensitising acridone chromophore (lambda exc = 410 nm) exhibits a 69% change in the intensity ratio of the 618/588 nm Eu emission bands between 5 and 15 mM HCO3- in a cell lysate medium.
ISSN:1359-7345
1364-548X
DOI:10.1039/b206286k