A General, Efficient, and Inexpensive Catalyst System for the Coupling of Aryl Iodides and Thiols

An efficient copper-catalyzed carbon−sulfur bond formation reaction was developed. This method is particularly noteworthy given its experimental simplicity, high generality, and exceptional level of functional group toleration and the low cost of the catalyst system.

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Bibliographic Details
Published in:Organic letters 2002-10, Vol.4 (20), p.3517-3520
Main Authors: Kwong, Fuk Yee, Buchwald, Stephen L
Format: Article
Language:English
Subjects:
Catalysis
Chemistry, Organic - economics
Copper - chemistry
Iodides - chemical synthesis
Iodides - chemistry
Molecular Structure
Sulfhydryl Compounds - chemical synthesis
Sulfhydryl Compounds - chemistry
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Description
Summary:An efficient copper-catalyzed carbon−sulfur bond formation reaction was developed. This method is particularly noteworthy given its experimental simplicity, high generality, and exceptional level of functional group toleration and the low cost of the catalyst system.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0266673