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A General, Efficient, and Inexpensive Catalyst System for the Coupling of Aryl Iodides and Thiols

An efficient copper-catalyzed carbon−sulfur bond formation reaction was developed. This method is particularly noteworthy given its experimental simplicity, high generality, and exceptional level of functional group toleration and the low cost of the catalyst system.

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Published in:Organic letters 2002-10, Vol.4 (20), p.3517-3520
Main Authors: Kwong, Fuk Yee, Buchwald, Stephen L
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Language:English
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description An efficient copper-catalyzed carbon−sulfur bond formation reaction was developed. This method is particularly noteworthy given its experimental simplicity, high generality, and exceptional level of functional group toleration and the low cost of the catalyst system.
doi_str_mv 10.1021/ol0266673
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Catalysis
Chemistry, Organic - economics
Copper - chemistry
Iodides - chemical synthesis
Iodides - chemistry
Molecular Structure
Sulfhydryl Compounds - chemical synthesis
Sulfhydryl Compounds - chemistry
title A General, Efficient, and Inexpensive Catalyst System for the Coupling of Aryl Iodides and Thiols
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