Mutation detection

The detection and characterization of mutations in genes has become a major area of interest in many areas of biology. Such variation may account for speciation, tumour formation, drug resistance, as well as the more obvious nature of inherited disease.

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Bibliographic Details
Published in:Nature (London) 1991-10, Vol.353 (6344), p.582-583
Main Authors: Cotton, R. G. H, Malcolm, A. D. B
Format: Article
Language:English
Subjects:
Animals
Base Sequence
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
DNA Mutational Analysis
Electrophoresis - methods
Fundamental and applied biological sciences. Psychology
Genes
Genetics of eukaryotes. Biological and molecular evolution
Humans
Hydrolysis
Nucleic Acid Denaturation
Oligonucleotide Probes
Polymerase Chain Reaction
Vertebrata
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Description
Summary:The detection and characterization of mutations in genes has become a major area of interest in many areas of biology. Such variation may account for speciation, tumour formation, drug resistance, as well as the more obvious nature of inherited disease.
ISSN:0028-0836
1476-4687
DOI:10.1038/353582a0