Intima-Media Thickness of the Common Carotid Arteries Is Related to Coronary Atherosclerosis and left Ventricular Hypertrophy in Older Adults

Increased intima-media thickness (IMT) of the common carotid arteries is related to generalized atherosclerosis and increased risk of future myocardial infarction and cerebrovascular disease. An association between IMT and the presence of coronary artery disease (CAD) has been documented, but contro...

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Bibliographic Details
Published in:Angiology 2002-09, Vol.53 (5), p.569-574
Main Authors: Raso, Francesco Mattace, van Popele, Nicole M., Schalekamp, Maarten A. D. H., van der Cammen, Tischa J. M.
Format: Article
Language:English
Subjects:
Age Factors
Aged
Atherosclerosis
Biological and medical sciences
Cardiology. Vascular system
Carotid artery diseases
Carotid Artery, Common - diagnostic imaging
Cohort Studies
Coronary Angiography
Coronary Artery Disease - complications
Coronary Artery Disease - diagnostic imaging
Coronary heart disease
Data Interpretation, Statistical
Diabetes Complications
Diagnosis
Echocardiography
Female
Heart
Humans
Hypercholesterolemia - complications
Hypertension - complications
Hypertrophy, Left Ventricular - complications
Hypertrophy, Left Ventricular - diagnostic imaging
Linear Models
Male
Medical sciences
Risk Factors
Smoking - adverse effects
Surveys and Questionnaires
Tunica Intima - diagnostic imaging
Tunica Media - diagnostic imaging
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Summary:Increased intima-media thickness (IMT) of the common carotid arteries is related to generalized atherosclerosis and increased risk of future myocardial infarction and cerebrovascular disease. An association between IMT and the presence of coronary artery disease (CAD) has been documented, but controversial data have been found about the relation between increased IMT and the extent of CAD. An association between carotid atherosclerosis and cardiac remodeling has also been reported. It is still unclear whether increased IMT of the common carotid arteries might be associated with prevalent cardiovascular disease in older adults. This study included 70 patients, 37 with CAD and 33 matched for age and gender without CAD. All patients underwent a baseline clinical examination, B-mode ultrasound of the carotid arteries, and echocardiography. The authors evaluated the possible association between increased IMT with the presence and extent of CAD and the presence of left ventricular hypertrophy (LVH). The patients with CAD had significantly increased IMT compared to patients without CAD. IMT was found to increase with the number of coronary vessels affected, after adjustment for age, gender, hypertension, hypercholesterolemia, diabetes mellitus, and smoking habits. The test for trend was highly significant (p
ISSN:0003-3197
1940-1574
DOI:10.1177/000331970205300511