Positron emission tomography, echo-doppler, and exercise studies of functional capacity in hypertensive heart disease

This study examines the relationship between functional capacity, left ventricular diastolic function, and myocardial perfusion reserve (MPR) in patients with left ventricular hypertrophy (LVH). We studied 16 patients with LVH and 10 controls. Functional capacity was assessed by cardiopulmonary exer...

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Bibliographic Details
Published in:American journal of hypertension 2002-10, Vol.15 (10), p.907-910
Main Authors: Akinboboye, Olakunle O, Idris, Olajide, Goldsmith, Rochelle, Berekashvili, Kati, Chou, R.u-Ling, Bergman, Steven R
Format: Article
Language:English
Subjects:
Adult
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Cohort Studies
Diastole
Echocardiography, Doppler
Exercise Test
Female
Humans
Hypertension
Hypertension - complications
hypertrophy
Hypertrophy, Left Ventricular - diagnostic imaging
Hypertrophy, Left Ventricular - etiology
Male
Medical sciences
Middle Aged
Oxygen Consumption
perfusion
Tomography, Emission-Computed
Vascular Resistance
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Summary:This study examines the relationship between functional capacity, left ventricular diastolic function, and myocardial perfusion reserve (MPR) in patients with left ventricular hypertrophy (LVH). We studied 16 patients with LVH and 10 controls. Functional capacity was assessed by cardiopulmonary exercise, MPR by positron emission tomography, and left ventricular diastolic function by echo-Doppler. Functional capacity and MPR were significantly lower in the patients. Functional capacity correlated positively with MPR and left ventricular diastolic function. Diminished functional capacity in patients with hypertension-induced LVH is related to the impairment in MPR and left ventricular diastolic function.
ISSN:0895-7061
1879-1905
1941-7225
DOI:10.1016/S0895-7061(02)02985-0