An Improved Catalyst for Ring-Closing Alkyne Metathesis Based on Molybdenum Hexacarbonyl/2-Fluorophenol

An improved “instant” catalyst for ring-closing alkyne metathesis reaction is described. Catalyst formed in situ from molybdenum hexacarbonyl and 2-fluorophenol can be used without exclusion of air and moisture and shows high activity in metathesis of functionalized diynes. This system allows cycliz...

Full description

Saved in:
Bibliographic Details
Published in:Organic letters 2002-10, Vol.4 (21), p.3747-3749
Main Authors: Grela, Karol, Ignatowska, Jolanta
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An improved “instant” catalyst for ring-closing alkyne metathesis reaction is described. Catalyst formed in situ from molybdenum hexacarbonyl and 2-fluorophenol can be used without exclusion of air and moisture and shows high activity in metathesis of functionalized diynes. This system allows cyclization of substrates which were incompatible with previously known Mo(CO)6/phenol catalysts.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol026690o