Biology of cancer and aging

The greatest risk factor for cancer is aging. Human cancer incidence increases exponentially with advancing age. Cancer growth rate and potential for metastatic spread may be influenced by age‐specific change in host response. Because cancer and aging are, thus, inextricably linked, the American Can...

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Bibliographic Details
Published in:Cancer 1991-12, Vol.68 (S11), p.2525-2526
Main Authors: Holmes, Frederick F., Wilson, John, Blesch, Karen Smith, Kaesberg, Paul R., Miller, Richard, Sprott, Richard
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aging - physiology
Humans
Incidence
Longevity
Neoplasms - epidemiology
Neoplasms - physiopathology
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Summary:The greatest risk factor for cancer is aging. Human cancer incidence increases exponentially with advancing age. Cancer growth rate and potential for metastatic spread may be influenced by age‐specific change in host response. Because cancer and aging are, thus, inextricably linked, the American Cancer Society should encourage submission of research proposals that address the mechanisms of aging and how aging alters cancer development.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19911201)68:11+<2525::AID-CNCR2820681508>3.0.CO;2-3