Loading…

Versatile computerized system for tracking and analysis of water maze tests

A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed. The goal of the present work was the automation of the Morris water maze test, one of the most popular behavioral methods for the study of an...

Full description

Saved in:
Bibliographic Details
Published in:Behavior research methods, instruments, & computers instruments, & computers, 2001-08, Vol.33 (3), p.371-380
Main Authors: Mukhina, T V, Bachurin, S O, Lermontova, N N, Zefirov, N S
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613
cites cdi_FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613
container_end_page 380
container_issue 3
container_start_page 371
container_title Behavior research methods, instruments, & computers
container_volume 33
creator Mukhina, T V
Bachurin, S O
Lermontova, N N
Zefirov, N S
description A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed. The goal of the present work was the automation of the Morris water maze test, one of the most popular behavioral methods for the study of animal memory. An original system was developed that provides fast and accurate tracking of animals, storage of the results in the database and video archive and a means of analyzing the results. This computerized version of the Morris water maze test permits the quantification of such vague characteristics of cognitive function as the "directionality" of search of the hidden platform after a standard training series. The suggested parameters made it possible to discriminate cognitive properties of the novel compounds from other behavioral effects affecting escape latency. The effectiveness of this system was demonstrated in two experiments with neurochemically lesioned and drug-treated rats.
doi_str_mv 10.3758/BF03195391
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72178699</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72178699</sourcerecordid><originalsourceid>FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613</originalsourceid><addsrcrecordid>eNpFkLFOwzAQhi0EoqWw8ADIEwNSwM7FsT1CRQFRiQVYI9c-o0DSFDtR1T49Rq3U4XTLp__--wi55OwWpFB3DzMGXAvQ_IiMuYA8E1qyYzJmsoAMFFMjchbjN2MMQOhTMuJcaM5KPSavnxii6esGqe3a1dBjqLfoaNzEHlvqu0D7YOxPvfyiZunSmGYT60g7T9cm0bQ1W6Q9xj6ekxNvmogX-z0hH7PH9-lzNn97epnezzObavaZLFDkXsMiB-VSi0Ir4wE8s5AzBwZKKDEvnLJSC-8Kh0qw9F0pFqBdyWFCrne5q9D9Duly1dbRYtOYJXZDrGTOpSq1TuDNDrShizGgr1ahbk3YVJxV_-qqg7oEX-1Th0WL7oDuXcEfD59oTA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72178699</pqid></control><display><type>article</type><title>Versatile computerized system for tracking and analysis of water maze tests</title><source>Springer Link</source><creator>Mukhina, T V ; Bachurin, S O ; Lermontova, N N ; Zefirov, N S</creator><creatorcontrib>Mukhina, T V ; Bachurin, S O ; Lermontova, N N ; Zefirov, N S</creatorcontrib><description>A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed. The goal of the present work was the automation of the Morris water maze test, one of the most popular behavioral methods for the study of animal memory. An original system was developed that provides fast and accurate tracking of animals, storage of the results in the database and video archive and a means of analyzing the results. This computerized version of the Morris water maze test permits the quantification of such vague characteristics of cognitive function as the "directionality" of search of the hidden platform after a standard training series. The suggested parameters made it possible to discriminate cognitive properties of the novel compounds from other behavioral effects affecting escape latency. The effectiveness of this system was demonstrated in two experiments with neurochemically lesioned and drug-treated rats.</description><identifier>ISSN: 0743-3808</identifier><identifier>EISSN: 1532-5970</identifier><identifier>DOI: 10.3758/BF03195391</identifier><identifier>PMID: 11591069</identifier><language>eng</language><publisher>United States</publisher><subject>Analysis of Variance ; Animals ; Behavior, Animal ; Behavioral Sciences - methods ; Computing Methodologies ; Maze Learning ; Observation - methods ; Rats ; Videotape Recording</subject><ispartof>Behavior research methods, instruments, &amp; computers, 2001-08, Vol.33 (3), p.371-380</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613</citedby><cites>FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11591069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mukhina, T V</creatorcontrib><creatorcontrib>Bachurin, S O</creatorcontrib><creatorcontrib>Lermontova, N N</creatorcontrib><creatorcontrib>Zefirov, N S</creatorcontrib><title>Versatile computerized system for tracking and analysis of water maze tests</title><title>Behavior research methods, instruments, &amp; computers</title><addtitle>Behav Res Methods Instrum Comput</addtitle><description>A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed. The goal of the present work was the automation of the Morris water maze test, one of the most popular behavioral methods for the study of animal memory. An original system was developed that provides fast and accurate tracking of animals, storage of the results in the database and video archive and a means of analyzing the results. This computerized version of the Morris water maze test permits the quantification of such vague characteristics of cognitive function as the "directionality" of search of the hidden platform after a standard training series. The suggested parameters made it possible to discriminate cognitive properties of the novel compounds from other behavioral effects affecting escape latency. The effectiveness of this system was demonstrated in two experiments with neurochemically lesioned and drug-treated rats.</description><subject>Analysis of Variance</subject><subject>Animals</subject><subject>Behavior, Animal</subject><subject>Behavioral Sciences - methods</subject><subject>Computing Methodologies</subject><subject>Maze Learning</subject><subject>Observation - methods</subject><subject>Rats</subject><subject>Videotape Recording</subject><issn>0743-3808</issn><issn>1532-5970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNpFkLFOwzAQhi0EoqWw8ADIEwNSwM7FsT1CRQFRiQVYI9c-o0DSFDtR1T49Rq3U4XTLp__--wi55OwWpFB3DzMGXAvQ_IiMuYA8E1qyYzJmsoAMFFMjchbjN2MMQOhTMuJcaM5KPSavnxii6esGqe3a1dBjqLfoaNzEHlvqu0D7YOxPvfyiZunSmGYT60g7T9cm0bQ1W6Q9xj6ekxNvmogX-z0hH7PH9-lzNn97epnezzObavaZLFDkXsMiB-VSi0Ir4wE8s5AzBwZKKDEvnLJSC-8Kh0qw9F0pFqBdyWFCrne5q9D9Duly1dbRYtOYJXZDrGTOpSq1TuDNDrShizGgr1ahbk3YVJxV_-qqg7oEX-1Th0WL7oDuXcEfD59oTA</recordid><startdate>20010801</startdate><enddate>20010801</enddate><creator>Mukhina, T V</creator><creator>Bachurin, S O</creator><creator>Lermontova, N N</creator><creator>Zefirov, N S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010801</creationdate><title>Versatile computerized system for tracking and analysis of water maze tests</title><author>Mukhina, T V ; Bachurin, S O ; Lermontova, N N ; Zefirov, N S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Analysis of Variance</topic><topic>Animals</topic><topic>Behavior, Animal</topic><topic>Behavioral Sciences - methods</topic><topic>Computing Methodologies</topic><topic>Maze Learning</topic><topic>Observation - methods</topic><topic>Rats</topic><topic>Videotape Recording</topic><toplevel>online_resources</toplevel><creatorcontrib>Mukhina, T V</creatorcontrib><creatorcontrib>Bachurin, S O</creatorcontrib><creatorcontrib>Lermontova, N N</creatorcontrib><creatorcontrib>Zefirov, N S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Behavior research methods, instruments, &amp; computers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mukhina, T V</au><au>Bachurin, S O</au><au>Lermontova, N N</au><au>Zefirov, N S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Versatile computerized system for tracking and analysis of water maze tests</atitle><jtitle>Behavior research methods, instruments, &amp; computers</jtitle><addtitle>Behav Res Methods Instrum Comput</addtitle><date>2001-08-01</date><risdate>2001</risdate><volume>33</volume><issue>3</issue><spage>371</spage><epage>380</epage><pages>371-380</pages><issn>0743-3808</issn><eissn>1532-5970</eissn><abstract>A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed. The goal of the present work was the automation of the Morris water maze test, one of the most popular behavioral methods for the study of animal memory. An original system was developed that provides fast and accurate tracking of animals, storage of the results in the database and video archive and a means of analyzing the results. This computerized version of the Morris water maze test permits the quantification of such vague characteristics of cognitive function as the "directionality" of search of the hidden platform after a standard training series. The suggested parameters made it possible to discriminate cognitive properties of the novel compounds from other behavioral effects affecting escape latency. The effectiveness of this system was demonstrated in two experiments with neurochemically lesioned and drug-treated rats.</abstract><cop>United States</cop><pmid>11591069</pmid><doi>10.3758/BF03195391</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0743-3808
ispartof Behavior research methods, instruments, & computers, 2001-08, Vol.33 (3), p.371-380
issn 0743-3808
1532-5970
language eng
recordid cdi_proquest_miscellaneous_72178699
source Springer Link
subjects Analysis of Variance
Animals
Behavior, Animal
Behavioral Sciences - methods
Computing Methodologies
Maze Learning
Observation - methods
Rats
Videotape Recording
title Versatile computerized system for tracking and analysis of water maze tests
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T05%3A08%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Versatile%20computerized%20system%20for%20tracking%20and%20analysis%20of%20water%20maze%20tests&rft.jtitle=Behavior%20research%20methods,%20instruments,%20&%20computers&rft.au=Mukhina,%20T%20V&rft.date=2001-08-01&rft.volume=33&rft.issue=3&rft.spage=371&rft.epage=380&rft.pages=371-380&rft.issn=0743-3808&rft.eissn=1532-5970&rft_id=info:doi/10.3758/BF03195391&rft_dat=%3Cproquest_cross%3E72178699%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c319t-74e52f93b238d106498af33f0c320d3a3636e24d8c795fd4de85053965b39d613%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=72178699&rft_id=info:pmid/11591069&rfr_iscdi=true