Sequential versus simultaneous biventricular resynchronization for severe heart failure: Evaluation by tissue Doppler imaging

Cardiac resynchronization therapy (CRT) by means of simultaneous biventricular pacing improves left ventricular systolic performance and synchrony in patients with heart failure and bundle-branch block. We used tissue tracking and 3D echocardiography to evaluate the impact of sequential CRT with ind...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2002-10, Vol.106 (16), p.2078-2084
Main Authors: SOGAARD, Peter, EGEBLAD, Henrik, PEDERSEN, Anders K, WON YONG KIM, KRISTENSEN, Bent Ø, HANSEN, Peter S, MORTENSEN, Peter T
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Bundle-Branch Block - diagnostic imaging
Bundle-Branch Block - therapy
Diseases of the cardiovascular system
Echocardiography, Doppler - methods
Echocardiography, Three-Dimensional - methods
Female
Follow-Up Studies
Heart Failure - diagnostic imaging
Heart Failure - physiopathology
Heart Failure - therapy
Heart Ventricles - diagnostic imaging
Humans
Male
Medical sciences
Myocardial Contraction
Pacemaker, Artificial
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
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Summary:Cardiac resynchronization therapy (CRT) by means of simultaneous biventricular pacing improves left ventricular systolic performance and synchrony in patients with heart failure and bundle-branch block. We used tissue tracking and 3D echocardiography to evaluate the impact of sequential CRT with individualized interventricular delay programming. Twenty consecutive patients with severe heart failure and left bundle-branch block were included. Tissue tracking and 3D echocardiography were carried out before and on the day after pacemaker implantation. Eleven different interventricular delays were examined in each patient. Patients were reexamined after 3 months. Simultaneous CRT immediately reduced the extent of myocardium displaying delayed longitudinal contraction (DLC) from 48.6+/-16% to 23.2+/-13% (P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.0000034512.90874.8E