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Synthesis and antimycobacterial activity of [5-(pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives
[5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed a feable activity against a strain of Mycobacterium tuberculosis and a strain of Mycobacterium avium.
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| Published in: | Farmaco (Società chimica italiana : 1989) 2001-08, Vol.56 (8), p.587-592 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c457t-20d6f8bf92a97fd26efef2988800a301edc45936f32a561a672382d7a7ce27653 |
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| cites | cdi_FETCH-LOGICAL-c457t-20d6f8bf92a97fd26efef2988800a301edc45936f32a561a672382d7a7ce27653 |
| container_end_page | 592 |
| container_issue | 8 |
| container_start_page | 587 |
| container_title | Farmaco (Società chimica italiana : 1989) |
| container_volume | 56 |
| creator | Mamolo, Maria Grazia Falagiani, Valeria Zampieri, Daniele Vio, Luciano Banfi, Elena |
| description | [5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed a feable activity against a strain of
Mycobacterium tuberculosis and a strain of
Mycobacterium avium. |
| doi_str_mv | 10.1016/S0014-827X(01)01097-7 |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 0014-827X |
| ispartof | Farmaco (Società chimica italiana : 1989), 2001-08, Vol.56 (8), p.587-592 |
| issn | 0014-827X 1879-0569 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72199921 |
| source | Elsevier:Jisc Collections:Elsevier Read and Publish Agreement 2022-2024:Freedom Collection (Reading list) |
| subjects | [5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antimycobacterial activity Biological and medical sciences Medical sciences Microbial Sensitivity Tests Mycobacterium - drug effects Pharmacology. Drug treatments Structure-Activity Relationship Thiadiazoles - chemical synthesis Thiadiazoles - chemistry Thiadiazoles - pharmacology |
| title | Synthesis and antimycobacterial activity of [5-(pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives |
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