Focal lobular spermatogenesis and pubertal acceleration associated with ipsilateral Leydig cell hyperplasia

Leydig cell tumors of the testis are the underlying cause in about 10% of the cases of precocious puberty in boys. Leydig cell hyperplasia is a less well-characterized cause, with an undocumented frequency. We describe a boy with precocious puberty associated with ipsilateral testicular enlargement...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2000-09, Vol.56 (3), p.508-509
Main Authors: Leung, Albert C, Kogan, Stanley J
Format: Article
Language:English
Subjects:
Biomarkers - blood
Child, Preschool
Humans
Hyperplasia - blood
Hyperplasia - complications
Hyperplasia - surgery
Leydig Cells - pathology
Male
Orchiectomy
Puberty, Precocious - blood
Puberty, Precocious - etiology
Puberty, Precocious - surgery
Spermatogenesis
Testosterone - blood
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Summary:Leydig cell tumors of the testis are the underlying cause in about 10% of the cases of precocious puberty in boys. Leydig cell hyperplasia is a less well-characterized cause, with an undocumented frequency. We describe a boy with precocious puberty associated with ipsilateral testicular enlargement and focal Leydig cell hyperplasia with spermatogenesis limited to the local adjacent testicular tissue.
ISSN:0090-4295
1527-9995
DOI:10.1016/S0090-4295(00)00636-1