Free radical scavenging activity of Lafoensia pacari

The methanolic extract of the stem bark of Lafoensia pacari (Lythraceae) showed free radical scavenging activity in the diphenyl picryl hydrazyl radical (DPPH) decoloration assay and inhibited the enzyme xanthine oxidase ‘in vitro’. Bioassay-guided isolation led to ellagic acid (EA) as the main acti...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2000-09, Vol.72 (1), p.173-178
Main Authors: Solon, Soraya, Lopes, Lousã, Teixeira de Sousa, Paulo, Schmeda-Hirschmann, Guillermo
Format: Article
Language:English
Subjects:
Alcohols
Biological and medical sciences
Brazil
Chromatography, High Pressure Liquid
DPPH
Ellagic acid
Free radical scavengers
Free Radical Scavengers - isolation & purification
Free Radical Scavengers - pharmacology
Free Radicals - chemistry
General pharmacology
Lafoensia pacari
Lythraceae
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Epidermis - chemistry
Plant Extracts - pharmacology
Plant Stems - chemistry
Plants, Medicinal - chemistry
Spectrophotometry, Ultraviolet
Water
Xanthine oxidase
Xanthine Oxidase - metabolism
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Summary:The methanolic extract of the stem bark of Lafoensia pacari (Lythraceae) showed free radical scavenging activity in the diphenyl picryl hydrazyl radical (DPPH) decoloration assay and inhibited the enzyme xanthine oxidase ‘in vitro’. Bioassay-guided isolation led to ellagic acid (EA) as the main active compound of Brazilian and Paraguayan collections of the plant.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(00)00233-6