Conscious sedation versus general anaesthesia for minilaparoscopic gamete intra-Fallopian transfer: a prospective randomized study

BACKGROUND: Gamete intra-Fallopian transfer (GIFT) is a successful technique for infertile women, and is performed almost exclusively by laparoscopy under general anaesthesia. METHODS: We performed a prospective randomized study of 67 infertile patients to assess the efficacy of minilaparoscopic GIF...

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Bibliographic Details
Published in:Human reproduction (Oxford) 2001-11, Vol.16 (11), p.2295-2297
Main Authors: Pellicano, Massimiliano, Zullo, Fulvio, Fiorentino, Agnese, Tommaselli, Giovanni A., Palomba, Stefano, Nappi, Carmine
Format: Article
Language:English
Subjects:
Adult
Anesthesia, General
Biological and medical sciences
Birth control
bupivacaine
Conscious Sedation
Female
Gamete Intrafallopian Transfer - methods
GIFT
Gynecology. Andrology. Obstetrics
Humans
Infertility - therapy
Laparoscopy
local anaesthesia
Medical sciences
minilaparoscopy
Pregnancy
Pregnancy Outcome
Prospective Studies
Sterility. Assisted procreation
Time Factors
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Summary:BACKGROUND: Gamete intra-Fallopian transfer (GIFT) is a successful technique for infertile women, and is performed almost exclusively by laparoscopy under general anaesthesia. METHODS: We performed a prospective randomized study of 67 infertile patients to assess the efficacy of minilaparoscopic GIFT under conscious sedation/local anaesthesia (group A) compared with general anaesthesia (group B). Operative and discharge times and pregnancy outcome were evaluated in both groups. RESULTS: Operative time was similar in both groups. The rate of patients discharged 2 h after surgery was significantly higher in group A. The necessity for postoperative analgesics was significantly higher in group B. No significant differences were noted between the two study groups in terms of pregnancy outcome. CONCLUSIONS: Conscious sedation and local anaesthesia will allow us to perform an outpatient minilaparoscopic GIFT without the need for general anaesthesia. The simplicity of the method, and the quicker discharge time in comparison with general anaesthesia, offer a detectable benefit for patients.
ISSN:0268-1161
1460-2350
1460-2350
DOI:10.1093/humrep/16.11.2295