The effects of cigarette smoking on the heterogeneity of ventricular repolarization

Background Although the circulatory effects of cigarette smoking have been studied extensively, its impact on ventricular repolarization has not been adequately evaluated. Methods The goal of our study was to determine whether cigarette smoking influences the spatial and temporal heterogeneity of ve...

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Bibliographic Details
Published in:The American heart journal 2001-11, Vol.142 (5), p.833-837
Main Authors: Dilaveris, Polychronis, Pantazis, Antonios, Gialafos, Elias, Triposkiadis, Filippos, Gialafos, John
Format: Article
Language:English
Subjects:
Adult
Age Factors
Biological and medical sciences
Drug addictions
Electrocardiography - statistics & numerical data
Heart Rate - physiology
Heart Ventricles
Humans
Male
Medical sciences
Sex Factors
Smoking - adverse effects
Smoking - physiopathology
Toxicology
Vectorcardiography - statistics & numerical data
Ventricular Dysfunction - diagnosis
Ventricular Dysfunction - physiopathology
Ventricular Function - physiology
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Summary:Background Although the circulatory effects of cigarette smoking have been studied extensively, its impact on ventricular repolarization has not been adequately evaluated. Methods The goal of our study was to determine whether cigarette smoking influences the spatial and temporal heterogeneity of ventricular repolarization in a population of young, healthy, male subjects. A digital 12-lead surface electrocardiogram was obtained from 1394 men recruited from the Hellenic Air Force and classified as smokers and nonsmokers. The maximum, minimum, and median QT intervals, QT dispersion (QT maximum – QT minimum), the rate-corrected maximum and median QT intervals, the slopes of the QT maximum/RR and QT median/RR regression equations, and the vectorcardiographic markers spatial T amplitude and spatial QRS-T angle were evaluated in the 2 groups. Results Heart rate was significantly higher (P
ISSN:0002-8703
1097-6744
DOI:10.1067/mhj.2001.118737