Egg allergy in infancy predicts respiratory allergic disease by 4 years of age

Sensitization to hen’s egg early in life has been proposed as a predictor for respiratory allergic disease during childhood. However, symptomatic egg allergy in infancy has not been studied in this context. In 1989, a cohort of consecutive births was recruited. Data on family history of atopy and en...

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Bibliographic Details
Published in:Pediatric allergy and immunology 2000-08, Vol.11 (3), p.162-167
Main Authors: Tariq, Syed M., Matthews, Sharon M., Hakim, Eluzai A., Arshad, Syed H.
Format: Article
Language:English
Subjects:
aero-allergen
Allergic diseases
allergy
Biological and medical sciences
Child, Preschool
Cohort Studies
egg
Female
Food Hypersensitivity - complications
Food Hypersensitivity - epidemiology
Forecasting
Humans
Immunopathology
Incidence
Infant
Male
Medical sciences
Ovum
Prospective Studies
Radioallergosorbent Test
respiratory
Respiratory and ent allergic diseases
Respiratory Hypersensitivity - etiology
sensitization
Skin Tests
United Kingdom - epidemiology
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Summary:Sensitization to hen’s egg early in life has been proposed as a predictor for respiratory allergic disease during childhood. However, symptomatic egg allergy in infancy has not been studied in this context. In 1989, a cohort of consecutive births was recruited. Data on family history of atopy and environmental factors were collected. At 4 years of age, 1218 children were seen of whom 981 were skin‐prick tested with a range of food and aero‐allergens. Of the 1218 children, 29 (2.4%) had suffered symptomatic egg allergy (20 during infancy). Egg allergy in infancy was associated with increased respiratory (asthma, rhinitis) allergic disease (odds ratio [OR] 5.0, 95% confidence intervals [CI] 1.1–22.3; p 
ISSN:0905-6157
1399-3038
DOI:10.1034/j.1399-3038.2000.00077.x