Merkel cell carcinoma of the parotid gland associated with Warthin tumour: report of two cases

Merkel cell carcinoma of the parotid gland associated with Warthin tumour: report of two cases Aims: Two cases of Merkel cell carcinoma occurring simultaneously and in close association with a Warthin tumour of the parotid gland are reported Methods and results: The patients were a 65‐year‐old man a...

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Bibliographic Details
Published in:Histopathology 2001-10, Vol.39 (4), p.342-346
Main Authors: Fornelli, A, Eusebi, V, Pasquinelli, G, Quattrone, P, Rosai, J
Format: Article
Language:English
Subjects:
Adenolymphoma - metabolism
Adenolymphoma - pathology
Adenolymphoma - ultrastructure
Aged
Biological and medical sciences
Carcinoma, Merkel Cell - metabolism
Carcinoma, Merkel Cell - pathology
Carcinoma, Merkel Cell - ultrastructure
Chromogranins - analysis
Humans
Immunohistochemistry
Intermediate Filament Proteins - analysis
Keratin-20
Male
Medical sciences
Merkel cell carcinoma
Microscopy, Electron
Otorhinolaryngology. Stomatology
parotid gland
Parotid Neoplasms - metabolism
Parotid Neoplasms - pathology
Parotid Neoplasms - ultrastructure
salivary glands
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
Warthin tumour
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Summary:Merkel cell carcinoma of the parotid gland associated with Warthin tumour: report of two cases Aims: Two cases of Merkel cell carcinoma occurring simultaneously and in close association with a Warthin tumour of the parotid gland are reported Methods and results: The patients were a 65‐year‐old man and a 70‐year‐old man, respectively. The Merkel cell carcinoma component was immunoreactive for chromogranin and keratin 20 and contained neuroendocrine‐type granules at the ultrastructural level. Conclusions: The histogenesis of this heretofore undescribed combination is discussed.
ISSN:0309-0167
1365-2559
DOI:10.1046/j.1365-2559.2001.01240.x