The Aggressiveness and Extent of Meningioma Imaged by Combined Fluorine-18 FDG and Positron Emission Tomography

A 52-year-old woman with recurrent left cavernous sinus meningioma had undergone partial resection 5 years earlier. She had progressive symptomatic enlargement of the residual tumor and was considering further resection and radiotherapy. Results of the initial fluorine-18 fluorodeoxyglucose positron...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 2000-09, Vol.25 (9), p.736-736
Main Authors: WONG, C OLIVER, BLEZA, MAXIMO V, DWORKIN, HOWARD J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Female
Fluorodeoxyglucose F18
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Meningeal Neoplasms - diagnostic imaging
Meningeal Neoplasms - pathology
Meningioma - diagnostic imaging
Meningioma - pathology
Middle Aged
Nervous system
Neurology
Radionuclide investigations
Radiopharmaceuticals
Tomography, Emission-Computed
Tumors of the nervous system. Phacomatoses
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 52-year-old woman with recurrent left cavernous sinus meningioma had undergone partial resection 5 years earlier. She had progressive symptomatic enlargement of the residual tumor and was considering further resection and radiotherapy. Results of the initial fluorine-18 fluorodeoxyglucose positron emission tomograph (F-18 FDG PET) obtained to judge tumor aggressiveness was negative, suggesting low-grade tumor. Sodium fluoride ion (F) was subsequently injected with a dose equal to the calculated residual F-18 FDG in the body. The combined F-18 FDG/F scan, performed 1 hour after F ion injection, revealed intense uptake by the deposition of F ion in the calcified tumor against background activity of F-18 FDG. This combined imaging protocol not only ensures exact coregistration of F and F-18 FDG but also increases the sensitivity for detecting recurrent tumor with low metabolism by the ubiquitous presence of calcification in this tumor. The combined protocol would be useful to show the extent and aggressiveness of this disease as it measures tumor metabolism and calcification.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-200009000-00023