Light and confocal laser-scanning microscopical evidences for complementary patterns of glial fibrillary acidic protein and Wisteria floribunda agglutinin labeled structures in human and rat brain

We investigated the pattern of glial fibrillary acidic protein (GFAP) and Wisteria floribunda agglutinin (WFA) labeled structures in the superior colliculus and in the somatosensory cortex of humans and rats of different age groups using immunohistochemical methods, light and confocal laser-scanning...

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Bibliographic Details
Published in:Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2000-08, Vol.52 (4), p.303-307
Main Authors: HILBIG, Heidegard, BIDMON, Hans-Jürgen, DINSE, Hubert, MÜLLER, Andrea, ZILLES, Karl
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Animals
Astrocytes - chemistry
Autopsy
Biological and medical sciences
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Female
Glial Fibrillary Acidic Protein - analysis
Glial Fibrillary Acidic Protein - chemistry
Humans
Immunohistochemistry
Lectins - analysis
Lectins - chemistry
Male
Medical sciences
Microscopy, Confocal
Microscopy, Polarization
Middle Aged
Neurology
Rats
Somatosensory Cortex - chemistry
Superior Colliculi - chemistry
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Summary:We investigated the pattern of glial fibrillary acidic protein (GFAP) and Wisteria floribunda agglutinin (WFA) labeled structures in the superior colliculus and in the somatosensory cortex of humans and rats of different age groups using immunohistochemical methods, light and confocal laser-scanning microscopy. We never found a double labeling of WFA and GFAP positive structures neither in the superior colliculus nor in the cortex of both man and rat. The complementary pattern of WFA and GFAP labeling was present both at the macroscopic and microscopic level. We found a clear prevalence of either WFA or GFAP expression in the arborization of the astrocytes as well as in the pattern of lamination.
ISSN:0940-2993
1618-1433