The current practice of intra-aortic balloon counterpulsation: results from the Benchmark Registry

• Published in: Journal of the American College of Cardiology 2001-11, Vol.38 (5), p.1456-1462
• Main Authors: Ferguson, James J, Cohen, Marc, Freedman, Robert J, Stone, Gregg W, Miller, Michael F, Joseph, Debra L, Ohman, E.Magnus
• Format: Article
• Language: English
• Subjects: Age Factors; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Angina, Unstable - therapy; Benchmarking - organization & administration; Biological and medical sciences; Cardiac Catheterization; Cardiopulmonary Bypass; Coronary Artery Bypass; Data Collection - methods; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care; Female; Guideline Adherence - standards; Guideline Adherence - statistics & numerical data; Hospital Mortality; Humans; Intensive care medicine; Intra-Aortic Balloon Pumping - adverse effects; Intra-Aortic Balloon Pumping - mortality; Intra-Aortic Balloon Pumping - standards; Intra-Aortic Balloon Pumping - statistics & numerical data; Male; Medical sciences; Middle Aged; Patient Selection; Practice Guidelines as Topic - standards; Practice Patterns, Physicians' - standards; Practice Patterns, Physicians' - statistics & numerical data; Predictive Value of Tests; Prospective Studies; Registries; Risk Factors; Shock, Cardiogenic - therapy; Treatment Outcome
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/S0735-1097(01)01553-4

OBJECTIVES This study presents clinical data from the first large registry of aortic counterpulsation, a computerized database that incorporates prospectively gathered data on indications for intra-aortic balloon counterpulsation (IABP) use, patient demographics, concomitant medication and in-hospital outcomes and complications. BACKGROUND The intra-aortic balloon pump (IABP) is widely used to provide circulatory support for patients experiencing hemodynamic instability due to myocardial infarction, cardiogenic shock, or in very high risk patients undergoing angioplasty or coronary artery bypass grafting. METHODS Between June 1996 and August 2000, 203 hospitals worldwide (90% U.S., 10% non-U.S.) collected 16,909 patient case records (68.8% men, 31.2% women; mean age 65.9 ± 11.7 years). RESULTS The most frequent indications for use of IABP were as follows: to provide hemodynamic support during or after cardiac catheterization (20.6%), cardiogenic shock (18.8%), weaning from cardiopulmonary bypass (16.1%), preoperative use in high risk patients (13.0%) and refractory unstable angina (12.3%). Major IABP complications (major limb ischemia, severe bleeding, balloon leak, death directly due to IABP insertion or failure) occurred in 2.6% of cases; in-hospital mortality was 21.2% (11.6% with the balloon in place). Female gender, high age and peripheral vascular disease were independent predictors of a serious complication. CONCLUSIONS This registry provides a useful tool for monitoring the evolving practice of IABP. In the modern-day practice of IABP, complication rates are generally low, although in-hospital mortality remains high. There is an increased risk of major complications in women, older patients and patients with peripheral vascular disease.