Low-dose dexamethasone effectively prevents postoperative nausea and vomiting after ambulatory laparoscopic surgery

To evaluate the prophylactic effect of low-dose dexamethasone (5 mg) on postoperative nausea and vomiting (PONV) in women undergoing ambulatory laparoscopic surgery. Metoclopramide and saline served as controls. One hundred twenty women (n=40 in each of the three groups) undergoing ambulatory laparo...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of anesthesia 2001-11, Vol.48 (10), p.973-977
Main Authors: HUANG, Jeng-Chai, SHIEH, Ja-Ping, TANG, Chao-Shun, TZENG, Jann-Inn, CHU, Koung-Shing, WANG, Jhi-Joung
Format: Article
Language:English
Subjects:
Adult
Ambulatory Surgical Procedures
Biological and medical sciences
Dexamethasone - therapeutic use
Digestive system
Double-Blind Method
Female
Humans
Laparoscopy
Medical sciences
Metoclopramide - therapeutic use
Nausea
Pharmacology. Drug treatments
Postoperative Nausea and Vomiting - prevention & control
Postoperative period
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the prophylactic effect of low-dose dexamethasone (5 mg) on postoperative nausea and vomiting (PONV) in women undergoing ambulatory laparoscopic surgery. Metoclopramide and saline served as controls. One hundred twenty women (n=40 in each of the three groups) undergoing ambulatory laparoscopic tubal ligation under general anesthesia were enrolled in this randomized, double-blinded, placebo-controlled study. After tracheal intubation, group I received i.v. dexamethasone 5 mg, whereas groups II and III received i.v. metoclopramide 10 mg and saline, respectively. Patients in group I reported a lower incidence of PONV and requested less rescue antiemetics than those in group III during the first four postoperative hours (P
ISSN:0832-610X
1496-8975
DOI:10.1007/BF03016586