Hierarchical Diagnosis in Chronic Schizophrenia: A Clinical Study of Co-occurring Syndromes

Co-occurring or associated psychiatric syndromes (APS) such as depression, obsessive-compulsive disorder (OCD), and panic disorder have largely been hidden from view by exclusion rules that prohibit their being diagnosed in the presence of schizophrenia. This article presents data from a clinical st...

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Bibliographic Details
Published in:Schizophrenia bulletin 2000, Vol.26 (3), p.517-525
Main Authors: Bermanzohn, Paul C, Porto, Linda, Arlow, Phyllis B, Pollack, Simcha, Stronger, Roslyn, Siris, Samuel G
Format: Article
Language:English
Subjects:
Adult
Chronic Disease
Clinical Trials as Topic
Comorbidity
Depressive Disorder, Major - complications
Depressive Disorder, Major - epidemiology
Female
Human
Humans
Major Depression
Male
Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder - complications
Obsessive-Compulsive Disorder - epidemiology
Outpatient
Panic Disorder
Panic Disorder - complications
Panic Disorder - epidemiology
Psychiatric Status Rating Scales
Schizophrenia
Schizophrenia - complications
Schizophrenia - diagnosis
Severity of Illness Index
Syndrome
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Summary:Co-occurring or associated psychiatric syndromes (APS) such as depression, obsessive-compulsive disorder (OCD), and panic disorder have largely been hidden from view by exclusion rules that prohibit their being diagnosed in the presence of schizophrenia. This article presents data from a clinical study of APS in chronic schizophrenia and reviews the relevant literature. Thirty-seven chronic schizophrenia patients consecutively admitted to a day program were administered the Structured Clinical Interview for Diagnosis for DSM-IV and the Yale-Brown Obsessive Compulsive Scale symptom checklist. Exclusion rules prohibiting the diagnosis of APS were bypassed. Eighteen patients (48.6%) had one or more APS. Ten patients (27%) had major depression. Eleven (29.7%) met criteria for OCD. Four patients (10.8%) met criteria for panic disorder. These findings suggest that APS may be common in chronic schizophrenia and that there is a need to study these syndromes' clinical validity, including their treatability. A research plan to study the validity of these syndromes further is discussed.
ISSN:0586-7614
1745-1701
DOI:10.1093/oxfordjournals.schbul.a033472