Coronary artery patency following long-term successful engraftment 14 years after bone marrow transplantation in the hurler syndrome

The coronary arteries in a patient with the Hurler Syndrome appear only minimally affected by the deposition of glycosaminoglycans 14 years after successful bone marrow engraftment. This finding is added to the previously reported salutary effects of transplant on large airways, cardiac function, he...

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Bibliographic Details
Published in:The American journal of cardiology 2001-11, Vol.88 (9), p.1075-1077
Main Authors: Braunlin, Elizabeth A., Rose, Alan G., Hopwood, John J., Candel, Rebeca D., Krivit, William
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood vessels
Bone marrow
Bone Marrow Transplantation
Bone marrow, stem cells transplantation. Graft versus host reaction
Child, Preschool
Constriction, Pathologic
Coronary vessels
Coronary Vessels - pathology
Coronary Vessels - physiology
Fatal Outcome
Female
Humans
Medical sciences
Mucopolysaccharidosis I - surgery
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Transplants & implants
Vascular Patency
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Description
Summary:The coronary arteries in a patient with the Hurler Syndrome appear only minimally affected by the deposition of glycosaminoglycans 14 years after successful bone marrow engraftment. This finding is added to the previously reported salutary effects of transplant on large airways, cardiac function, hepatic morphology, and central nervous system function.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(01)01999-3